The notion of the “biological individual” is crucial to studies of genetics, immunology, evolution,development, anatomy, and physiology. Each of these biological subdisciplines has a specific conception of individuality, which has historically provided conceptual contexts for integrating newly acquired data. During the past decade, nucleic acid analysis, especially genomic sequencing and high-throughput RNA techniques, has challenged each of these disciplinary definitions by finding significant interactions of animals and plants with symbiotic microorganisms that disrupt the boundaries that heretofore had characterized the biological individual. Animals cannot be considered individuals by anatomical or physiological criteria because a diversity of symbionts are both present and functional in completing metabolic pathways and serving other physiological functions. Similarly, these new studies have shown that animal development is incomplete without symbionts. Symbionts also constitute a second mode of genetic inheritance, providing selectable genetic variation for natural selection. The immune system also develops, in part, in dialogue with symbionts and thereby functions as a mechanism for integrating microbes into the animal-cell community. Recognizing the “holobiont”—the multicellular eukaryote plus its colonies of persistent symbionts—as a critically important unit of anatomy, development, physiology, immunology, and evolution opens up new investigative avenues and conceptually challenges the ways in which the biological subdisciplines have heretofore characterized living entities.
Stress is ubiquitous and on the rise. How we learn to manage it can have profound effects on our health and well being. This series explains how our bodies experience stress and demonstrates effective strategies to help you thrive in a fast-paced world. On this edition, Margaret Kemeny, UCSF professor of psychiatry, focuses on identifying the links between psychological factors, the immune system and health and illness. Series: UCSF Mini Medical School for the Public [2/2008] [Health and Medicine] [Show ID: 13722]
Can a person literally die of loneliness? Is there such a thing as a “”cancer personality””? Drawing on scientific research and the author’s decades of experience as a practicing physician, this book provides answers to these and other important questions about the effect of the mind-body link on illness and health and the role that stress and one’s individual emotional makeup play in an array of common diseases.
- Explores the role of the mind-body link in conditions and diseases such as arthritis, cancer, diabetes, heart disease, IBS, and multiple sclerosis
- Draws on medical research and the author’s clinical experience as a family physician
- Includes The Seven A’s of Healing-principles of healing and the prevention of illness from hidden stress
Shares dozens of enlightening case studies and stories, including those of people such as Lou Gehrig (ALS), Betty Ford (breast cancer), Ronald Reagan (Alzheimer’s), Gilda Radner (ovarian cancer), and Lance Armstrong (testicular cancer)
An international bestseller translated into fifteen languages, When the Body Says No promotes learning and healing, providing transformative insights into how disease can be the body’s way of saying no to what the mind cannot or will not acknowledge.